Summarized by Masters of Longevity from Nature - Biotechnology.
Small molecules raised iCM colony formation; 3D ECM mechanics shaped outcomes.
Key Takeaways
- Small molecules increased colony formation in Matrigel and PEG.
- Softer, faster-degrading PEG hydrogels favored early colony formation.
- PEG colonies were rarely contractile unless transferred to Matrigel.
