Preclinical research exploring a novel cell-surface engineering strategy to bolster regenerative erectile dysfunction therapy. Readers gain translational and methodological insights.
Key Takeaways
- Surface-engineered mesenchymal stromal cells displayed enhanced cavernosal retention and survival in vivo
- Polydopamine nanoparticle coating mitigated reactive oxygen species damage and improved inflammation locally
- Engineered cells reversed tissue pathology and restored erectile function in rat and beagle models