Summarized by Masters of Longevity from Nature - Main.
Diet and antibiotics interplay: a clinical and experimental article examining how simple-sugar–rich diets influence gut microbiome disruption during antibiotic treatment, offering implications for dietary guidance and microbiome-sparing strategies.
Key Takeaways
- In 158 hematopoietic cell transplant patients, sugar intake during antibiotic exposure predicted a 24.1% additional mean decrease in faecal α-diversity per 100 g consumed.
- Combined sugar and antibiotic exposure was associated with community domination by pathobionts, notably Enterococcus faecium.
- Mouse experiments showed that sucrose supplementation increased and prolonged antibiotic-driven Enterococcus expansion.
