Longevity News

Short-term efficacy and safety of recombinant human adenovirus type 5 combined with PD-1 immune checkpoint inhibitors and SOX regimen in neoadjuvant therapy of locally advanced gastric cancer: a retrospective study

Source: Frontiers - Health • Published: 15 Jul 2026, 00:00

Short-term efficacy and safety of recombinant human adenovirus type 5 combined with PD-1 immune checkpoint inhibitors and SOX regimen in neoadjuvant therapy of locally advanced gastric cancer: a retrospective study

Neoadjuvant treatment options for locally advanced gastric cancer are examined, presenting a retrospective evaluation of a combined viral, immunotherapy, and chemotherapy approach. Readers will find an accessible preview of study design, safety focus, and clinical relevance for preoperative strategies.

Key Takeaways
  • After patients completed two cycles of neoadjuvant treatment
  • Primary endpoint of the study was the postoperative pathological response rate (pCR)
  • In previous clinical studies showed immunotherapy combined with targeted therapy
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