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Serum LRG1 as a non-invasive biomarker for identifying complex coronary anatomy in pre-angiography risk stratification

Source: Frontiers - Health • Published: 04 Jun 2026, 00:00

Serum LRG1 as a non-invasive biomarker for identifying complex coronary anatomy in pre-angiography risk stratification

Evaluate a blood biomarker for non-invasive pre-angiography risk stratification of complex coronary anatomy and predictive model performance.

Key Takeaways
  • LRG1 was significantly overexpressed in AMI patients versus controls in GEO datasets
  • In 138 CAD patients, serum LRG1 levels were higher in AMI than non‑AMI
  • Logistic model including LRG1 and LDL‑C improved prediction and showed clinical net benefit
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