Sequence-defined polymers promise a primer on precision-engineered non-viral gene delivery systems, outlining methods and multidisciplinary design strategies.
Key Takeaways
- Sequence-defined polymers enable precise control of monomer composition, charge distribution and functionality
- Advanced synthesis routes include solid-phase methods, flow chemistry and supramolecular templating
- Integrating synthesis, imaging and computation is proposed to accelerate translation to reliable non-viral vectors