Assessment of plasma p-tau217 as a long-term prognostic biomarker for progression from cognitive normality to clinical impairment.
Key Takeaways
- One such marker is phosphorylated tau 217 (p-tau217)
- As the mechanisms of neurodegeneration are already operating at a higher than average level in their brain cells
- Tau becomes pathological and damaging when it is hyperphosphorylated