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Prognostic value and clinical net benefit of global longitudinal strain in sepsis: a prospective study with internal bootstrap validation

Source: Frontiers - Health • Published: 22 Jul 2026, 00:00

Prognostic value and clinical net benefit of global longitudinal strain in sepsis: a prospective study with internal bootstrap validation

Assessment of speckle-tracking global longitudinal strain for early detection and prognostic stratification of sepsis-related myocardial dysfunction and mortality risk.

Key Takeaways
  • Formulated GLS-SOFA nomogram showed excellent calibration upon 1,000-bootstrap internal validation
  • Validated GLS-SOFA nomogram and decision curve models provide a practical
  • GLS_AVG strongly correlated with SOFA ( r = 0.663) and NT-proBNP peak ( r = 0.424)
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