Environmental plasticizer exposure studied via integrated computational and laboratory approaches. Readers can expect multi-omics and experimental exploration of prostate cancer links.
Key Takeaways
- Study identified 183 genes linking common plasticizers to prostate cancer
- PLK1, ALB, and CCNA2 were narrowed as core prognostic targets using machine learning
- DMP increased prostate cancer cell proliferation, migration, invasion and upregulated PLK1 expression