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Photochemical internalization enhances in vivo immunity to peptide‑ and protein‑based vaccines with synthetic dsRNA adjuvants

Source: Nature - Biotechnology • Published: 09 Aug 2026, 00:00

Photochemical internalization enhances in vivo immunity to peptide‑ and protein‑based vaccines with synthetic dsRNA adjuvants

Photochemical internalization as a strategy to boost immune responses to peptide- and protein-based vaccines paired with synthetic dsRNA adjuvants; a research article preview inviting readers to learn how this method was evaluated in preclinical models.

Key Takeaways
  • Please note there may be errors present which affect the content, and all legal disclaimers apply
  • Despite the use of potent innate immune adjuvants such as synthetic double‑stranded RNA (dsRNA)
  • PCI combined with the SIINFEKL peptide and poly(I:C)
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