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Performance comparison of machine learning models for risk prediction of post-craniotomy nausea and vomiting: A retrospective study

Source: Frontiers - Health • Published: 07 Aug 2026, 00:00

Performance comparison of machine learning models for risk prediction of post-craniotomy nausea and vomiting: A retrospective study

Assessment and temporal validation of four machine learning models to predict post-craniotomy nausea and vomiting risk and compare clinical utility.

Key Takeaways
  • LightGBM achieved the best overall performance with highest accuracy, recall, F1-score, and AUC
  • LASSO selected 14 core predictors from 768 craniotomy patient samples for model development
  • Random Forest showed marked performance decline on temporal validation, indicating likely overfitting
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