Reports an oral nano-emulsion prodrug of a gut microbial metabolite that preserves CD8+ T cell stemness and boosts antitumor immunity in mouse models.
Key Takeaways
- By utilizing an in vitro screening of these altered non-SCFA metabolites on inulin gel administration
- Demonstrated how to improve the drug-like properties of microbial metabolites
- As small-molecule prodrugs have been widely used in modern pharmaceutics