Longevity News

Optimization and bioactivity assessment of Sparassis crispa extracts with response surface methodology and artificial neural network-genetic algorithm

Source: Nature - Biotechnology • Published: 08 Jul 2026, 00:00

Optimization and bioactivity assessment of Sparassis crispa extracts with response surface methodology and artificial neural network-genetic algorithm

Sparassis crispa extracts are examined in a study comparing extraction-optimization methods. Readers get analytical and cell-based bioactivity profiling.

Key Takeaways
  • ANN-GA optimized extract showed higher TAS, DPPH, and FRAP values
  • ANN-GA extract exhibited lower TOS and OSI than the RSM extract
  • ANN-GA extract contained higher levels of phenolics including gallic, caffeic, and protocatechuic acids
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