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Ocular manifestations and immunological profiles of thyroid eye disease with lacrimal gland enlargement

Source: Frontiers - Health • Published: 15 Jul 2026, 00:00

Ocular manifestations and immunological profiles of thyroid eye disease with lacrimal gland enlargement

Reports MRI-defined lacrimal gland enlargement in thyroid eye disease and compares ocular signs with immune and serologic profiles across patients.

Key Takeaways
  • 36 of 123 TED patients had lacrimal gland enlargement on MRI compared with 87 without enlargement
  • ELG patients showed worse proptosis, shorter TBUT, and higher Schirmer I test values
  • Serum TPO-Ab levels and peripheral Treg cell proportions independently correlated with lacrimal gland area
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