A research update links age-related peroxisome loss to mitochondrial decline and describes how preventing peroxisome degradation preserves organelle health and lifespan in worms.
Key Takeaways
- Decline in number of peroxisomes modestly accelerates the pace of aging
- Despite their centrality to cell biology, the relevance of peroxisomes to aging remains understudied
- Here, we further investigated how prx-11 inhibition promotes longevity