Synthesis of microRNA roles, diagnostics, delivery platforms, and precision medicine strategies for periodontal disease research and translational potential.
Key Takeaways
- MiR-146a, miR-155, and miR-223 were prioritized across multiple studies for periodontal disease diagnosis
- These miRNAs are detectable in saliva and gingival crevicular fluid as non-invasive biomarkers
- Preclinical hydrogels and nanoparticle delivery of anti-miRs and mimics reduced inflammation and repaired bone