Summarized by Masters of Longevity from Neuroscience News.
In mice, 24 hours of high‑fat diet produced divergent synaptic changes in LH neurons.

Key Takeaways
- A single day of high‑fat diet altered LH synaptic transmission in mice.
- In males, excitatory inputs onto appetite‑suppressing LH neurons were weakened.
- In females, inhibitory GABAergic inputs onto those LH neurons were weakened.



