Longevity News

Individualized osilodrostat treatment for patients with ACTH-dependent Cushing's syndrome: real-world evidence

Source: Frontiers - Health • Published: 22 Jun 2026, 00:00

Individualized osilodrostat treatment for patients with ACTH-dependent Cushing's syndrome: real-world evidence

Review of real-world dosing strategies, treatment patterns, and clinical outcomes for pharmacologic management of ACTH-dependent Cushing's syndrome.

Key Takeaways
  • Osilodrostat achieved therapeutic biochemical control in 92% of patients within 14 days
  • Morning cortisol normalized in 92% of patients and urinary cortisol in 75%
  • Eighteen of twenty patients with diabetes reduced antidiabetic medications or insulin
Read Original Source