Examines pooled evidence linking gout and hyperuricemia to male sexual and reproductive outcomes, summarizing clinical data and hormone findings.
Key Takeaways
- Meta-analysis included 104,277 patients with gout or hyperuricemia and 342,621 control subjects
- Patients with gout had higher erectile dysfunction risk with RR = 1.37, 95% CI 1.14–1.65
- Gout or hyperuricemia associated with lower testosterone and estradiol levels compared with controls