Longevity News

GLP-1 Receptor Agonists Slow Epigenetic Aging, a Measure of the Harms Done by Excess Visceral Fat

Source: Fight Aging! • Published: 15 Jun 2026, 10:22

GLP-1 Receptor Agonists Slow Epigenetic Aging, a Measure of the Harms Done by Excess Visceral Fat

Examination of clinical data linking calorie-reduction weight-loss treatments to changes in epigenetic aging and visceral fat–related risk markers.

Key Takeaways
  • Trial analyzed 108 adults with HIV-associated abdominal fat randomized to active or placebo injections
  • Treatment slowed biological aging pace by 9% as measured by DunedinPACE
  • Epigenetic clocks tied to inflammation and multiple organ risks also showed significant slowing
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