How peripheral monocyte states and erythrocyte alpha-synuclein patterns may clinically differentiate early Parkinsonism subtypes in peripheral blood.
Key Takeaways
- While MSA-P patients exhibited more rapid progression and severe autonomic failure
- Early-stage PD monocytes exhibited a profile of precise homeostatic regulation and protective mitochondrial adaptation
- Given that MSA exhibits a significantly more rapid clinical progression and poorer prognosis compared to PD