Longevity News

Fasting as a Path to Longevity: The Facts | Lifespan with Dr. David Sinclair - Season 2, Episode 2

Source: Youtube — David Sinclair • Published: 30 Jun 2026, 03:50

Fasting as a Path to Longevity: The Facts | Lifespan with Dr. David Sinclair - Season 2, Episode 2

How calorie restriction and fasting influence aging biology and metabolic risk, presented with research context and practical considerations.

Key Takeaways
  • Calorie restriction reduced mortality by an estimated 10 to 15% in one study
  • Calorie-restricted mice lived about 28% longer than controls in animal studies
  • Bile acid LCA mimicked calorie restriction effects while microbiome changes negated those benefits
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