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Fabrication and characterisation of hydroxypropyl methylcellulose/ethyl cellulose/polyvinylpyrrolidone based composite wafers as an anti-bacterial dressing: a promising approach for curcumin delivery

Source: Nature - Biotechnology • Published: 17 Jul 2026, 00:00

Fabrication and characterisation of hydroxypropyl methylcellulose/ethyl cellulose/polyvinylpyrrolidone based composite wafers as an anti-bacterial dressing: a promising approach for curcumin delivery

Reports a novel porous polymer wafer that loads curcumin for sustained antibacterial wound dressing and controlled local drug delivery.

Key Takeaways
  • Wafers were fabricated from HPMC, ethyl cellulose, and PVP K30 with curcumin dispersed by high-speed homogenization
  • In vitro testing showed sustained curcumin release while maintaining moist wound conditions and high exudate absorption
  • Disc diffusion assays demonstrated the wafers have measurable antibacterial activity against tested pathogens
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