Longevity News

Extraction and structural characterization of functional β-glucan from Wuping Ganoderma sinense and its immunomodulatory activity on mouse Raw 264.7 macrophages

Source: Nature - Biotechnology • Published: 13 Jul 2026, 00:00

Extraction and structural characterization of functional β-glucan from Wuping Ganoderma sinense and its immunomodulatory activity on mouse Raw 264.7 macrophages

Characterization of a fungal beta-glucan's structure and physicochemical properties and its immunomodulatory effects on macrophages in vitro.

Key Takeaways
  • Extraction yield was 0.41 mg per gram with 98.15% purity
  • WGG had average molecular weight 8.22×10^4 Da and 3:1 branching ratio
  • WGG increased RAW 264.7 proliferation, phagocytosis, and NO, TNF-α, IL-6 secretion concentration-dependently
Read Original Source