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Efficacy of First-line Treatment in Driver Gene-Negative Non-Small Cell Lung Cancer with Liver Metastases: A Bayesian Network Meta-analysis

Source: Frontiers - Health • Published: 12 Jun 2026, 00:00

Efficacy of First-line Treatment in Driver Gene-Negative Non-Small Cell Lung Cancer with Liver Metastases: A Bayesian Network Meta-analysis

Assess comparative first-line treatments for driver gene-negative NSCLC with liver metastases using a Bayesian network meta-analysis of randomized trials.

Key Takeaways
  • PD-1 inhibitor plus chemotherapy reduced progression risk versus chemotherapy alone (HR 0.572)
  • Combination also lowered overall mortality versus chemotherapy alone (HR 0.681)
  • Camrelizumab plus chemotherapy had top SUCRA values for PFS (84.18%) and OS (96.38%)
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