Reports a preclinical perinatal study assessing an adsorbed reduced‑antigen DTP vaccine's safety and antibody transfer in a rat model.
Key Takeaways
- Maternal dosing produced no treatment‑related maternal systemic toxicity or adverse reproductive outcomes
- High antigen‑specific antibody titers developed in dams and were passively transferred to F1 offspring
- No negative effects were observed on offspring survival, morphology, or early neuro‑reflex milestone acquisition