Longevity News

Editorial: The mouth as a diagnostic window: unveiling the systemic implications of oral health

Source: Frontiers - Health • Published: 07 Jul 2026, 00:00

Editorial: The mouth as a diagnostic window: unveiling the systemic implications of oral health

The oral cavity as a systemic diagnostic interface, synthesizing seven articles on inflammation, microbiome, and biomarkers.

Key Takeaways
  • Orthodontic mechanical stress raised NETs and IL-1β and IL-8 levels in saliva
  • Periodontitis correlated with leukoaraiosis and elevated systemic soluble TWEAK levels
  • Tooth loss associated with increased all-cause mortality mediated partly by hs-CRP
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