Examines melatonin's role as an accessible adjunct to manage chronic musculoskeletal pain and its link with sleep disruption.
Key Takeaways
- Meta-analysis of 23 randomized trials including 2,028 adults reported about nine point pain reductions
- Chronic pain doses typically ranged three to ten milligrams, with three milligrams most common
- Reported side effects matched placebo and no serious adverse events were observed