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Development of synthetic bacteriophages with extended host range to overcome resistant Klebsiella pneumoniae

Source: Nature - Biotechnology • Published: 26 Jun 2026, 00:00

Development of synthetic bacteriophages with extended host range to overcome resistant Klebsiella pneumoniae

Examination of engineered bacteriophage libraries that broaden host range to tackle multidrug-resistant hospital pathogens and phage resistance dynamics.

Key Takeaways
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  • Klebsiella pneumoniae (Kp) is a leading cause of bacterial nosocomial infections
  • We engineered synthetic bacteriophage variants using two in-house phage isolates
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