Longevity News

Development of a novel phage-displayed fusion protein of newcastle disease virus as a highly specific antigen for serological assays

Source: Nature - Biotechnology • Published: 20 Jul 2026, 00:00

Development of a novel phage-displayed fusion protein of newcastle disease virus as a highly specific antigen for serological assays

Describes a phage-display method producing a fusion-protein antigen for specific, scalable serological detection of Newcastle disease antibodies in poultry.

Key Takeaways
  • Phage-displayed immunodominant region of the NDV F protein was developed as a diagnostic antigen
  • Displayed antigen detected NDV-GVII-specific antibodies in vaccinated chicken serum samples
  • ELISA results using the phage antigen significantly correlated with hemagglutination inhibition test outcomes
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