Genome engineering: discover a feature about a single-cell editing workflow that helps researchers tackle edits in sensitive cell models.
Key Takeaways
- CellEDIT workflow enabled isoform-specific dermokine knockouts in fragile human keratinocytes
- Multi-omics analysis showed dermokine regulates keratinocyte differentiation and cell-cell adhesion
- Results were validated in chronic wound patient tissue, linking mechanisms to real-world repair challenges