Evaluation of defined extracellular matrix coatings for maintaining human neural progenitor properties on electrically conductive neural interfaces.
Key Takeaways
- Collagen IV supported hNPC viability and progenitor marker expression better than other coatings
- Collagen IV enhanced ERK/MAPK signaling, implicating integrin-mediated adhesion in survival
- Collagen IV coated ITO retained conductivity while preserving hNPC identity during electrical stimulation