Longevity News

Body composition-derived principal components partially explain sex and age effects on bone mineral density in type 2 diabetes mellitus

Source: Frontiers - Health • Published: 03 Jun 2026, 00:00

Body composition-derived principal components partially explain sex and age effects on bone mineral density in type 2 diabetes mellitus

Examine how composite body composition patterns explain sex and age differences in bone mineral density among type 2 diabetes patients and a diagnostic nomogram.

Key Takeaways
  • This contributes to reduced quality of life and heightened healthcare demand in affected individuals
  • Body composition is considered a key determinant of BMD in T2DM ( 5 – 7 )
  • Combined physiological effects of muscle-metabolic and fat-obesity components on BMD remain unclear
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