Assess marine-derived exopolysaccharide effects on cellular insulin resistance and associated metabolic and oxidative markers in a HepG2 model.
Key Takeaways
- AVP1 is a mannogalactan of approximately 16.2 kDa with mannose to galactose ratio 1:2.4
- AVP1 improved insulin sensitivity and increased glucose consumption in palmitate-induced HepG2 cells
- AVP1 lowered total cholesterol and triglycerides while reducing ROS and lipid peroxidation markers