Read about research that reframes a major Alzheimer's-linked protein as a protective cellular guardian and explores implications for neuronal maintenance.
Key Takeaways
- Binding to dangerous leaked nuclear material and ejecting it from the neuron via lysosomal exocytosis
- Utilizing an expansive experimental framework spanning human iPSC-derived neurons
- APP is best known as the protein from which Aβ peptides are generated through enzymatic cleavage