Tumour-derived organoid biobank story inviting readers to a research feature describing a large, clinically annotated resource and its scientific scope.
Key Takeaways
- Study generated 256 renewable, clinically annotated tumour organoids from five cancer types
- Genome-wide CRISPR–Cas9 screens across 162 organoids mapped gene dependencies and vulnerabilities
- Matched pre- and post-treatment paired models revealed targetable changes following tumour evolution