Covers how gut microbiota–bile acid signaling alters liver macrophage uptake and thereby changes nanomedicine biodistribution and tumor delivery.
Key Takeaways
- Clinical efficacy of nanomedicines is often limited by hepatic sequestration
- Gut-bacteria-derived bile acids induce Kupffer cell phagocytosis
- Repository is supported by NIH grants U2C-DK119886 and OT2-OD030544