Longevity News

A List of Interventions Known to Reduce Epigenetic Age in Humans

Source: Fight Aging! • Published: 26 Jun 2026, 18:16

A List of Interventions Known to Reduce Epigenetic Age in Humans

Curious which human-tested strategies shift modern epigenetic age measures? This review surveys studies, methods, and comparative responsiveness across interventions.

Key Takeaways
  • Systematic review identified 41 human studies testing next-generation epigenetic clocks
  • Semaglutide, caloric restriction, exercise, omega-3s, and umbilical cord plasma decreased epigenetic age
  • Nicotinamide riboside, rapamycin, and senolytics showed no detectable epigenetic clock effects
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