Examination of how gut microbiome composition influences host inflammatory responses and the risk of sepsis in experimental models.
Key Takeaways
- Murine survival after Acinetobacter baumannii infection depended on gut microbiota composition
- Colonization with Sangeribacter muris KT1-3 induced TLR4-dependent hyperinflammatory sepsis in mice
- Lethal susceptibility transferred to other mice via fecal transplantation and co-housing