Overview

1. Executive Summary (Confidence: High)

Liom (formerly known as Spiden) is a leading innovator in the $160 billion+ wearable health market, recently achieving a monumental technical breakthrough in Raman spectroscopy miniaturization.[48] Headquartered in Pfäffikon, Switzerland, the company has secured a total of $80 million in funding to date, including a $16. million Series A extension in late 2025.[48] Liom’s "world-first" achievement is the development of a calibration-free, non-invasive glucose-monitoring wearable that fits within a standard smartwatch form factor while maintaining a >24-hour battery life.[49] Clinical results published in 2025 demonstrate a Mean Absolute Relative Difference (MARD) of 14.5%, placing its accuracy on par with first-generation invasive CGMs.[52] Led by serial entrepreneur Leo Grünstein and supported by a board including Marc Maurer (former co-CEO of On Running), Liom is poised to disrupt the metabolic health sector when it launches its consumer device in 2028.[48] The following table summarizes Liom’s technical and commercial milestones.

Feature

Liom Technology

Current State-of-the-Art

Improvement

Calibration

Zero Needles

Requires Finger-sticks

Breakthrough

Form Factor

Smartwatch

Table-sized Lab Devices

12x Miniaturization

Accuracy (MARD)

14.5%

10-15% (Invasive CGMs)

Comparable (Non-invasive)

Biomarkers

Glucose, Lactate, Ketones

Mostly HR/Oxygen

Broadened Palette

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