Summarized by Masters of Longevity from Youtube — Siim Land.
Summarizes human clinical evidence on how omega-3 fatty acids affect inflammation, skin UV response, oxidation concerns, and glycation.

Key Takeaways
- An umbrella meta-analysis of 32 meta-analyses across over 100 randomized controlled trials found omega-3 supplementation reduced inflammatory markers like CRP, IL-6, and TNF-α.
- Controlled human trials show omega-3s incorporated into cell membranes lower arachidonic-acid-derived inflammatory signaling and produce pro-resolving mediators.
- Clinical trials report omega-3 intake does not increase UV susceptibility and instead reduces UV-induced redness and cellular damage in skin.



