Summarized by Masters of Longevity from Frontiers - Health.
Reports a community cohort analysis linking an integrated triglyceride-glucose–BMI index to ultrasound-defined diastolic dysfunction and its relative importance via machine learning.
Key Takeaways
- Higher TyG-BMI was associated with worse echocardiographic diastolic parameters including elevated left atrial volume index and higher E/e' ratio.
- Participants in the high TyG-BMI group had higher blood pressure, triglycerides, fasting glucose, and lower HDL-C compared with the low group.
- The high versus low TyG-BMI classification remained independently associated with ultrasound-defined diastolic dysfunction after extensive multivariable adjustment.
