Summarized by Masters of Longevity from Fight Aging!.
Topical urolithin A: a science-focused article about a skin-aging intervention that examines mitochondrial and cellular effects across models and early clinical tests.
Key Takeaways
- Topical urolithin A increased mitophagy and mitochondrial respiration in 2D, 3D, and ex vivo human skin models.
- Randomized placebo-controlled trials showed reduced periorbital wrinkle depth after eight weeks of topical urolithin A use.
- Topical urolithin A lowered UVB-induced erythema and decreased inflammatory and senescence-associated signaling in skin transcriptomics.
