Summarized by Masters of Longevity from Aging Cell.
Skeletal muscle–derived extracellular vesicles and their role in signaling to other organs during aging, previewing experimental perspectives and implications.
Key Takeaways
- Aging skeletal muscle releases extracellular vesicles with altered cargo compared with young muscle.
- Muscle-derived vesicles were shown to reach and influence at least one distant organ in experimental models.
- Changes in vesicle content correlated with age-related functional shifts in recipient tissues.
