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Serum glutathione and 4-hydroxynonenal profiles in relation to diabetic kidney disease severity and progression: a multicenter cross-sectional study and a longitudinal cohort

Source: Frontiers - Health • Published: 13 Nov 2026, 00:00

Summarized by Masters of Longevity from Frontiers - Health.

Lower GSH and higher 4-HNE were associated with DKD progression.

Serum glutathione and 4-hydroxynonenal profiles in relation to diabetic kidney disease severity and progression: a multicenter cross-sectional study and a longitudinal cohort
Key Takeaways
  • Lower GSH was associated with higher progression risk.
  • Higher 4-HNE was associated with greater DKD severity.
  • A combined biomarker score improved progression discrimination accuracy.
Read the full article at Frontiers - Health ↗

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