News summary

Serotonin Signals Suppress Physical Activity in Aging Mice

Source: Lifespan.io • Published: 13 Nov 2026, 18:12

Summarized by Masters of Longevity from Lifespan.io.

Stimulating dorsal raphe serotonin neurons cut movement and speed in aged mice.

Serotonin Signals Suppress Physical Activity in Aging Mice
Key Takeaways
  • Serotonin neuron firing was higher in older mice during active periods.
  • Targeted serotonin stimulation reduced movement without changing food intake.
  • Ablating dorsal raphe serotonin neurons increased activity and reduced fat.
Read the full article at Lifespan.io ↗

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