Summarized by Masters of Longevity from Neuroscience News.
A study identifies excess asparagine synthetase as an unintended stress trigger that halts neuronal growth in Angelman syndrome and reverses deficits in mice.
Key Takeaways
- Blocking this downstream enzyme restored normal brain development and behavior in mice.
- Yi and his team generated cell models lacking the functional UBE3A gene.
- Under ordinary physiological conditions, asparagine synthetase is harmless.
