Summarized by Masters of Longevity from Neuroscience News.
Rapamycin and brain blood flow: a short, human pilot-study article examining whether low-dose treatment can change cerebral perfusion and related physiology in genetically at-risk adults.
Key Takeaways
- A four-week low-dose daily rapamycin regimen increased cerebral blood flow only in APOE4 carriers.
- Female APOE4 carriers showed the largest perfusion improvements compared with male carriers.
- The study also reported rapamycin-associated shifts in metabolic, inflammatory, and gut microbiome measures.
