Summarized by Masters of Longevity from medRxiv.
Physical frailty as a predictor: a research article examining whether frailty forecasts a wide range of future chronic diseases and faster multimorbidity buildup over time.
Key Takeaways
- In 466,864 UK Biobank participants, physical frailty was linked to increased risk for 458 of 536 incident chronic diseases.
- Pre-frailty and frailty predicted faster annual multimorbidity accumulation versus robustness with betas 0.266 and 0.941 respectively.
- Frailty-associated accelerated multimorbidity was consistent across baseline burden and across neurodegenerative, metabolic, and psychiatric patterns.
