Summarized by Masters of Longevity from Lifespan.io.
This article previews research on how physical activity and a hormone-receptor drug may slow ovarian aging in mice, explaining experimental approaches and implications.
Key Takeaways
- One month of treadmill exercise preserved primordial follicles and reduced follicle loss in adult female mice.
- Adiponectin deficiency blunted exercise's protective effect, and ovary-specific adiponectin knockout reduced protection by 76%.
- AdipoRon treatment increased primordial and total follicle counts, AMH levels, and reduced ovarian p-mTOR signaling.
